The principal cytochrome P450 isoenzyme included appears being CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Close to eighty five% of an oral dose seems within the urine within 24 hrs of administration, most as the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity info.Protection